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ACE Signalling

The angiotensin converting enzyme (ACE) is a key regulatory enzyme within the renin angiotensin system and catalyses ... more

Chronic Kidney Disease

Chronic kidney diesease (CKD), characterized by a persistent reduction of glomerular filtration rate, is a common ... more

Endothelial Cell Signalling

Production of nitric oxide (NO) by the endothelial NO synthase (eNOS) is a pivotal phenomenon ... more

Lipid Signalling

Interest in the vascular cytochrome P450 (CYP)/soluble epoxide hydrolase (sEH) signalling cascade has increased ... more

Lipidrafts

Biological membranes contain functional domains with high concentration of cholesterol ... more

Long non coding RNAs (lncRNAs)

Until very recently, RNA was believed to primarily function as a messenger of genetic information from DNA to proteins. ... more

NADPH Oxidase

NADPH oxidases are the most important source of reactive oxygen species (ROS) in the vasculature ... more

Platelet Physiology

Diabetes mellitus is a major risk factor for vascular diseases and it is well accepted that the morbidity ... more

The polarity protein Scribble

Cell polarity represents a fundamental characteristics of many cell types essential for their function ... more

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